1. The pain may occur due to the expanding tumor pressing nerve and surrounding blood vessels, immune and inflammatory reactions against growing cancers, and pain is also caused by fear or anxiety.
2. Bleeding or discharge is not normal, such as saliva, coughing or vomiting blood, persistent nosebleeds, nipple fluid that contains blood, fluid hole coitus bleeding (between menstrual / menopause) blood in the stool, blood in the urine.
3. Changes in bowel habit
4. Losing weight rapidly due to lack of fat and protein (kaheksia)
5. A lump in the breast
6. Indigestion, such as difficulty swallowing constant.
7. Deaf, or the voice - the voice in the ear settled.
8. The wound is not healed - healed
9. Change the skin mole or striking
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